First, check bliss is actually running. Next, if bliss is running, try http://127.0.0.1:3220 instead.
Windows 7 (and later versions, so also Windows 8) introduced a change where 'localhost' (which means the computer that you are accessing bliss from) is discovered by asking your network, rather than trusting your local computer. If your network is not correctly configured, it may return the incorrect location. '127.0.0.1' forces your local computer to be used.
Also, in some cases anti-virus software can stop the bliss user interface loading.
Any other FAQs I forgot or clarifications required? Post your ideas below!